1、The effect of biological and chemical fertilizers on protein content in Artemisia annua L. leaves

In order to consider biological fertilizers (Nitroxin, Bio-phosphorus and Vermicompost) and chemical fertilizers (N, P) on protein content Artemisia annua L., we had done an experiment in Zabol University green house in 2011.

2、A review of various efforts to increase artemisinin and other antimalarial compounds in Artemisia Annua L plant

Dried leaf and herbal tea of Artemisia annua, also known as sweet wormwood, sweet annie, sweet sagewort—taken as a whole in its natural form or extract thereof, are one of the new hopes for treatment and prevention of malaria poor yet malaria burden countries in the world.

3、The Biosynthesis of Artemisinin (Qinghaosu) and the Phytochemistry of Artemisia annua L. (Qinghao)

The Chinese medicinal plant Artemisia annua L. (Qinghao) is the only known source of the sesquiterpene artemisinin (Qinghaosu), which is used in the treatment of malaria.

Isolation of Artemisinin (Qinghaosu) from Artemisia annua Growing in the United States

Instant determination of the artemisinin from various Artemisia annua L . extracts by LC‐ESI‐MS/MS and their in‐silico modelling and in vitro antiviral activity studies against SARS‐CoV‐2.

Qinghaosu (artemisinin): Chemistry and pharmacology

Early pharmacological and clinic studies showed QHS have rapid onset of action, low toxicity and high effect on both drug-resistant and drug-sensitive malaria. However, its shortcomings (poor...

Enhancement of artemisinin concentration and yield in response to optimization of nitrogen and potassium supply to Artemisia annua

Maximization of artemisinin yield (amount per plant) requires optimization of plant biomass via control of nitrogen nutrition.

On the possible role of qinghao acid in the biosynthesis of artemisinin

This review article focuses on the progress achieved during the last years in the production of artemisinin from Artemisia annua. The structure, biosynthesis and analysis of artemisinin and its mode of action are described.

Artemisinin: An Endoperoxidic Antimalarial from Artemisia annua L.

For thousands of years, physicians in China have treated fever with a decoction of the plant qinghao (1). In 1972 Chinese chemists isolated the active febrifuge from this plant, determining its structure, 1, by single crystal x-ray crystallography (2, 3). The...

Integrating medicinal plants extraction into a high

This is demonstrated for Artemisia annua L. currently cultivated or harvested in the wild for extraction of a single compound, artemisinin, comprising on average 1 wt% dry weight of the plant biomass.

Full article: Enhanced artemisinin accumulation and metabolic profiling of transgenic Artemisia annua L. plants over

Therefore, transgenic lines of A. annua L. plants over-expressing both HMG-Co A reductase (hmgr) and amorpha-4, 11-diene synthase (ads) genes were developed to enhance the content of artemisinin.

Artemisia annua, commonly known as Qinghao, is a traditional Chinese herb valued for its detoxifying, blood-cooling, and hemostatic properties. In agricultural practice, it can also be utilized as an organic fertilizer to enhance soil fertility and improve soil structure. Below is a detailed guide on processing Qinghao into fertilizer:

I. Collection and Initial Processing

1. Harvesting Time: Qinghao has a long growing cycle, typically spanning from spring to autumn. The optimal harvest period is during peak growth, such as late spring or early summer.
2. Harvesting Methods: Collect Qinghao carefully to avoid damaging the plants. Harvest either by cutting the aerial parts or uprooting the entire plant.
3. Preliminary Processing: Remove impurities (e.g., debris, wilted leaves) from the harvested Qinghao to prepare it for further processing.

II. Drying and Pulverization

1. Air Drying: Spread the processed Qinghao in a well-ventilated area for sun drying. Drying time varies depending on weather and temperature, usually ranging from several days to one week.
2. Oven Drying: Transfer the dried Qinghao to a dryer. Adjust temperature and duration based on the plant’s variety and quality to preserve its active ingredients.
3. Pulverization: Crush the dried Qinghao into fine particles. The powdered form can be applied directly or mixed with other organic fertilizers.

III. Fermentation Processing

1. Composting Method: Mix the powdered Qinghao with organic materials like farm manure or straw, then compost. During composting, microorganisms break down the active components into nutrients.
2. Fermentation Accelerators: Add starter cultures (e.g., yeast, lactic acid bacteria) to speed up decomposition and enhance fertilizer efficacy.
3. Fermentation Duration: Composting typically takes several weeks to months, depending on material quality and environmental conditions. Longer fermentation improves nutrient conversion and fertilizer effectiveness.

IV. Packaging and Storage

1. Packaging Materials: Use sealed plastic bags, woven sacks, or airtight containers to store the fermented Qinghao fertilizer. Ensure moisture and air are excluded.
2. Storage Conditions: Store in a cool, dry place away from direct sunlight and humidity. Prevent mold growth by avoiding damp environments.
3. Shelf Life: The fertilizer remains viable for approximately one year. Before use, check for discoloration, odor, or spoilage.

V. Key Considerations

1. Environmental Compliance: Follow local laws and eco-friendly practices during harvest and processing to minimize environmental impact.
2. Balanced Application: Apply Qinghao fertilizer according to soil and crop needs. Avoid overuse to prevent fertilizer burn or soil imbalance.
3. Compatibility: Do not mix with alkaline fertilizers, as this may reduce efficacy.

processed Qinghao serves as a green, soil-enriching organic fertilizer. Proper use enhances soil structure, boosts crop growth, and aligns with sustainable agricultural practices. Always apply thoughtfully to maximize benefits while avoiding excess.